Gynecomastia is not physically harmful, but in some cases can be an indicator of other more dangerous underlying conditions. Growing glandular tissue , typically from some form of hormonal stimulation, is often tender or painful.
Furthermore, it can frequently present social and psychological difficulties for the sufferer.
Weight loss can alter the condition in cases where it is triggered by obesity, but losing weight will not reduce the glandular component and patients cannot target areas for weight loss.
Massive weight loss can result in sagging tissues about the chest, chest ptosis , or drooping chest.